FEZF1 antibody (C-Term)

Catalog No. ABIN2784171

This anti-FEZF1 antibody is a Rabbit Polyclonal antibody detecting FEZF1 in WB and IHC. Suitable for Human, Guinea Pig, Horse, Rat and Rabbit.

Quick Overview for FEZF1 antibody (C-Term) (ABIN2784171)

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Reactivity: Human, Guinea Pig, Horse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEZF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FEZF1 Antibody

Binding Specificity: C-Term

Sequence: CPTCGKGFCR NFDLKKHVRK LHDSSLGLAR TPAGEPGTEP PPPLPQQPPM

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FEZF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FEZF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FEZF1

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Alternative Name: FEZF1

Background: FEZF1 is a transcription repressor. It is involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). It plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression of the FEZF1 is required in OSN to cell-autonomously regulate OSN axon projections. FEZF1 regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. It may be required for correct rostral migration of the interneuron progenitors.
Alias Symbols: ZNF312B, FEZ
Protein Interaction Partner: GABRR1, SP1,
Protein Size: 471

Molecular Weight: 52 kDa

Gene ID: 389549

NCBI Accession: NM_001024613, NP_001019784

UniProt: A0PJY2