ING4 antibody (Middle Region)

Catalog No. ABIN2784250

The Rabbit Polyclonal anti-ING4 antibody is suitable to detect ING4 in samples from Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for ING4 antibody (Middle Region) (ABIN2784250)

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ING4 Antibody

Binding Specificity: Middle Region

Sequence: DLKEKQIESS DYDSSSSKGK KSRTQKEKKA ARARSKGKNS DEEAPKTAQK

Predicted Reactivity: Cow: 100%, Dog: 87%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against ING4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ING4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ING4

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Alternative Name: ING4

Background: ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Alias Symbols: MGC12557, my036, p29ING4
Protein Interaction Partner: NAV2, GADD45A, SUV39H1, RELA, CDC34, HIST3H3, MSX1, TP53, PADI4, ING4, KAT7, JADE1, UBC, HIST1H3A, TLX3, JADE2, HOXB9, Trp53, EGLN1, G3BP2, PPFIA1, UBE2D2, EP300, HHT2, HHT1, HIST2H3C, JADE3, MEAF6, CDKN2A,
Protein Size: 248

Molecular Weight: 28 kDa

Gene ID: 51147

NCBI Accession: NM_016162, NP_057246

UniProt: Q9UNL4