DNER antibody (Middle Region)

Catalog No. ABIN2784322

The Rabbit Polyclonal anti-DNER antibody has been validated for WB. It is suitable to detect DNER in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit.

Quick Overview for DNER antibody (Middle Region) (ABIN2784322)

Target: DNER (delta/notch-Like EGF Repeat Containing (DNER))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNER antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNER Antibody

Binding Specificity: Middle Region

Sequence: DACQRKPCQN NASCIDANEK QDGSNFTCVC LPGYTGELCQ SKIDYCILDP

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DNER. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DNER

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 454 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNER

Target: DNER (delta/notch-Like EGF Repeat Containing (DNER))

Alternative Name: DNER

Background: DNER is an activator of the NOTCH1 pathway. It may mediate neuron-glia interaction during astrocytogenesis.
Alias Symbols: UNQ26, bet
Protein Interaction Partner: AP1G1,
Protein Size: 454

Molecular Weight: 50 kDa

Gene ID: 92737

NCBI Accession: NM_139072

UniProt: Q8NFT8

Pathways: Skeletal Muscle Fiber Development