DCP1B antibody (N-Term)

Catalog No. ABIN2784340

This Rabbit Polyclonal antibody specifically detects DCP1B in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse and Pig.

Quick Overview for DCP1B antibody (N-Term) (ABIN2784340)

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCP1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DCP1B Antibody

Binding Specificity: N-Term

Sequence: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 617 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DCP1B

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Alternative Name: DCP1B

Background: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-844 AY146652.1 1-844 845-2079 BC015368.2 379-1613 2080-2105 AW204088.1 3-28 c
Alias Symbols: DCP1, hDcp1b
Protein Interaction Partner: EDC3, ZFP36, UBC, E2F7, DCP1A, EDC4, PPM1A, DDX6, DCP2, KANK2, PNRC1, BAG4, EXOSC6, XRN1, LSM8, UPF2, SMAD4, HSPA1L, USP4,
Protein Size: 617

Molecular Weight: 68 kDa

Gene ID: 196513

NCBI Accession: NM_152640, NP_689853

UniProt: Q8IZD4