SUV420H1 antibody (C-Term)

Catalog No. ABIN2784480

This anti-SUV420H1 antibody is a Rabbit Polyclonal antibody detecting SUV420H1 in WB and ChIP. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SUV420H1 antibody (C-Term) (ABIN2784480)

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUV420H1 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-SUV420H1 Antibody

Binding Specificity: C-Term

Sequence: FINHDCRPNC KFVSTGRDTA CVKALRDIEP GEEISCYYGD GFFGENNEFC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against Suv420h1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUV420H1

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Alternative Name: Suv420h1

Background: Suv420h1 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. It mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins.
Alias Symbols: AA117471, C630029K18Rik, KMT5B, MGC18702, Suv4-20h1
Protein Interaction Partner: Rbl2, Rbl1, Rb1, Cbx1,
Protein Size: 327

Molecular Weight: 35 kDa

Gene ID: 225888

NCBI Accession: NM_001167884, NP_001161356