GABARAP antibody (N-Term)

Catalog No. ABIN2784490

Product Details anti-GABARAP Antibody

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IRKKYPDRVP VIVEKAPKAR IGDLDKKKYL VPSDLTVGQF YFLIRKRIHL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABARAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABARAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 117 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Alternative Name: GABARAP (GABARAP Products)

Background: Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABA(A) receptor-associated protein (GABARAP) is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Alias Symbols: FLJ25768, MGC120154, MGC120155, MM46, ATG8A
Protein Interaction Partner: MUL1, UBC, SQSTM1, TAX1BP1, NBR1, ATG101, ATG13, SRPK2, SRPK1, MAPK15, MLH1, BNIP3L, KATNB1, RB1CC1, ULK2, ULK1, OPTN, TBC1D25, DVL2, ATG7, FKBP4, MAP1LC3C, DYX1C1, NCOA7, MAP1LC3B, TBC1D15, ATG3, PI4K2A, ANKFY1, GABARAPL1, ATG4B, FNBP1, GABARAPL2, TECPR2
Protein Size: 117

Molecular Weight: 14 kDa

Gene ID: 11337

NCBI Accession: NM_007278, NP_009209

UniProt: O95166

Pathways: Autophagy