TNNI2 antibody (N-Term)

Catalog No. ABIN2784492

The Rabbit Polyclonal anti-TNNI2 antibody has been validated for WB. It is suitable to detect TNNI2 in samples from Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Goat, Horse and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for TNNI2 antibody (N-Term) (ABIN2784492)

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Goat, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNNI2 Antibody

Binding Specificity: N-Term

Sequence: PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against TNNI2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 182 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TNNI2 antibody (ABIN2784492)

Wang, Luo, Sun, Deng, Li, Tao, Hu, Gong: "[Inhibitory effect of N-terminal 24 amino acids of the p55 gamma, a regulatory subunit of phosphoinositide 3-kinase, on proliferation of colon carcinoma cell line HT29]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 10, pp. 1034-8, (2008) (PubMed).

Target Details for TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Alternative Name: TNNI2

Background: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Alias Symbols: AMCD2B, DA2B, FSSV, fsTnI
Protein Interaction Partner: TRIM63, TRIM55, UPF2, RORB, HNF4G, ESRRA, PKD2L1, TNNC1, TNNC2, TNNT3, TNNT1, CALM1, ACTB,
Protein Size: 182

Molecular Weight: 21 kDa

Gene ID: 7136

NCBI Accession: NM_003282, NP_003273

UniProt: P48788