PEG10 antibody (C-Term)

Catalog No. ABIN2784508

The Rabbit Polyclonal anti-PEG10 antibody has been validated for WB. It is suitable to detect PEG10 in samples from Human, Mouse, Rabbit, Pig, Cow, Horse, Dog and Guinea Pig.

Quick Overview for PEG10 antibody (C-Term) (ABIN2784508)

Target: PEG10 (Paternally Expressed 10 (PEG10))

Reactivity: Human, Mouse, Rabbit, Pig, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEG10 Antibody

Binding Specificity: C-Term

Sequence: RKPRSPPRAL VLPHIASHHQ VDPTEPVGGA RMRLTQEEKE RRRKLNLCLY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against PEG10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PEG10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Alternative Name: PEG10

Background: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.
Alias Symbols: EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Protein Interaction Partner: SIAH1, FAM127C, LDOC1, CALCOCO2, FAM127A, UBC, MAPT, HNRNPUL1, HNRNPH1, BAG1, TGFBR2, TGFBR1, BMPR1B, BMPR1A, ACVRL1, ACVR2B, ACVR2A, ACVR1B, ACVR1, RNF2, ZNF512B, RNF181, HMGCS1, TOLLIP, IRF4, SIAH2,
Protein Size: 401

Molecular Weight: 44 kDa

Gene ID: 23089

NCBI Accession: NM_001172438, NP_001165909