PLG antibody (Middle Region)
Quick Overview for PLG antibody (Middle Region) (ABIN2784539)
Target
See all PLG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- LISPEWVLTA AHCLEKSPRP SSYKVILGAH QEVNLEPHVQ EIEVSRLFLE
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Predicted Reactivity
- Dog: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 79%
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Characteristics
- This is a rabbit polyclonal antibody against PLG. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PLG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 810 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PLG (Plasminogen (PLG))
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Alternative Name
- PLG
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Background
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The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin
Alias Symbols: DKFZp779M0222
Protein Interaction Partner: RELA, SUZ12, RNF2, HSPD1, HSPB1, HSPA1A, ACTB, YTHDC1, CYFIP2, PRDX4, SMAD4, SMAD3, EP300, MAPK14, RBBP6, RAP2A, CDCP1, RUVBL1, TFPI2, NGF, CHGA, SERPING1, SERPINB13, CPB2, SERPINI1, F2RL1, LAMA3, MEP1A, PCOLCE, AMOT, SERPINF2, KNG1, F10, C7, PLAU, THBS1,
Protein Size: 810 -
Molecular Weight
- 88 kDa
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Gene ID
- 5340
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NCBI Accession
- NM_000301, NP_000292
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UniProt
- P00747
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Pathways
- Complement System, Lipid Metabolism
Target
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