TBL1Y antibody (Middle Region)

Catalog No. ABIN2784572

This Rabbit Polyclonal antibody specifically detects TBL1Y in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for TBL1Y antibody (Middle Region) (ABIN2784572)

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1Y antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBL1Y Antibody

Binding Specificity: Middle Region

Sequence: LASGSFDKYV HIWNTQSGSL VHSYQGTGGI FEVCWNARGD KVGASASDGS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TBL1Y. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBL1Y

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 522 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBL1Y

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Alternative Name: TBL1Y

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein.
Alias Symbols: TBL1
Protein Interaction Partner: SUZ12,
Protein Size: 522

Molecular Weight: 57 kDa

Gene ID: 90665

NCBI Accession: NM_033284, NP_150600

UniProt: Q9BQ87