INTS4 antibody (Middle Region)

Catalog No. ABIN2784574

This anti-INTS4 antibody is a Rabbit Polyclonal antibody detecting INTS4 in WB. Suitable for Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Dog, Horse and Zebrafish (Danio rerio).

Quick Overview for INTS4 antibody (Middle Region) (ABIN2784574)

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTS4 Antibody

Binding Specificity: Middle Region

Sequence: PAEVVKILQT MLRQSAFLHL PLPEQIHKAS ATIIEPAGES DNPLRFTSGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against INTS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human INTS4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 963 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS4

Target: INTS4 (Integrator Complex Subunit 4 (INTS4))

Alternative Name: INTS4

Background: INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].
Alias Symbols: INT4, MGC16733, MST093
Protein Interaction Partner: USHBP1, ZMIZ2, HGS, UBC, HECW2, INTS9, UBD, SUMO2, INTS10, SHFM1, INTS5, INTS3, INTS6, INTS1, RPAP2, KIAA0513,
Protein Size: 963

Molecular Weight: 108 kDa

Gene ID: 92105

NCBI Accession: NM_033547, NP_291025

UniProt: Q96HW7

Pathways: SARS-CoV-2 Protein Interactome