DPH2 antibody (N-Term)

Catalog No. ABIN2784710

This anti-DPH2 antibody is a Rabbit Polyclonal antibody detecting DPH2 in WB. Suitable for Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig and Horse.

Quick Overview for DPH2 antibody (N-Term) (ABIN2784710)

Target: DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPH2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPH2 Antibody

Binding Specificity: N-Term

Sequence: CLSPPARPLP VAFVLRQRSV ALELCVKAFE AQNPDPKAPV VLLSEPACAH

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against DPH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DPH2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 489 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPH2

Target: DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

Alternative Name: DPH2

Background: This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DPH2L2
Protein Interaction Partner: UBC, IL17A, BAG3, MMS19,
Protein Size: 489

Molecular Weight: 52 kDa

Gene ID: 1802

NCBI Accession: NM_001384, NP_001375

UniProt: Q9BQC3