ACTR3 antibody (N-Term)
Quick Overview for ACTR3 antibody (N-Term) (ABIN2784770)
Target
See all ACTR3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- IAIKESAKVG DQAQRRVMKG VDDLDFFIGD EAIEKPTYAT KWPIRHGIVE
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against ACTR3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACTR3
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 418 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ACTR3 (ARP3 Actin-Related Protein 3 (ACTR3))
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Alternative Name
- ACTR3
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Background
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The specific function of this gene has not yet been determined, however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
Alias Symbols: ARP3
Protein Interaction Partner: SUMO2, SUMO3, UBC, CALU, TP53RK, PUS1, FKBP10, NIF3L1, RPRD1B, UGGT1, DNAAF5, NSUN2, SH3GLB1, TPRKB, KIAA1279, TNPO3, TTLL12, ANP32B, ARPC2, ACTR2, ARPC1B, ARPC4, ARPC5, ZPR1, FUBP1, TPD52L2, SH3GL1, RPA1, RANGAP1, PRKACB, PPP1R12A, METTL1, HNRNPF, JUND,
Protein Size: 418 -
Molecular Weight
- 47 kDa
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Gene ID
- 10096
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NCBI Accession
- NM_005721, NP_005712
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UniProt
- P61158
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Pathways
- RTK Signaling, Regulation of Actin Filament Polymerization
Target
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