HRSP12 antibody (N-Term)

Catalog No. ABIN2784783

The Rabbit Polyclonal anti-HRSP12 antibody has been validated for WB. It is suitable to detect HRSP12 in samples from Human, Rabbit, Dog, Horse, Cow and Goat.

Quick Overview for HRSP12 antibody (N-Term) (ABIN2784783)

Target: HRSP12 (Heat-Responsive Protein 12 (HRSP12))

Reactivity: Human, Rabbit, Dog, Horse, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRSP12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRSP12 Antibody

Binding Specificity: N-Term

Sequence: MSSLIRRVIS TAKAPGAIGP YSQAVLVDRT IYISGQIGMD PSSGQLVSGG

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against HRSP12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HRSP12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 137 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRSP12

Target: HRSP12 (Heat-Responsive Protein 12 (HRSP12))

Alternative Name: HRSP12

Background: HRSP12 is an endoribonuclease responsible for the inhibition of the translation by cleaving mRNA.HRSP12 inhibits cell-free protein synthesis. HRSP12 cleaves phosphodiester bonds only in single-stranded RNA.
Alias Symbols: P14.5, PSP, UK114
Protein Interaction Partner: HRSP12, TMEM176A, SPEN, DEAF1, SERPINA5, COX2, MDM2, HPD, HIVEP1, MRPL53, SRPRB, SUGP1, SEPT9, SF3B4, PQBP1, SCO2, RBMS1, NDUFA7, UBC, TRIB3,
Protein Size: 137

Molecular Weight: 14 kDa

Gene ID: 10247

NCBI Accession: NM_005836, NP_005827

UniProt: P52758