NET1 antibody (N-Term)

Catalog No. ABIN2784784

This Rabbit Polyclonal antibody specifically detects NET1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit and Pig.

Quick Overview for NET1 antibody (N-Term) (ABIN2784784)

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NET1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NET1 Antibody

Binding Specificity: N-Term

Sequence: RGDHRSPASA QKFSSRSTVP TPAKRRSSAL WSEMLDITMK ESLTTREIRR

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NET1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NET1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 542 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NET1

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Alternative Name: NET1

Background: NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. It may be involved in activation of the SAPK/JNK pathway.
Alias Symbols: ARHGEF8, NET1A
Protein Interaction Partner: UBC, ELAVL1, MAGI1, DLG1, PRKAB2, USP11, RHOA,
Protein Size: 542

Molecular Weight: 62 kDa

Gene ID: 10276

NCBI Accession: NM_005863, NP_005854

UniProt: Q5SQI7

Pathways: Neurotrophin Signaling Pathway