PPIH antibody (Middle Region)

Catalog No. ABIN2784802

The Rabbit Polyclonal anti-PPIH antibody has been validated for WB. It is suitable to detect PPIH in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae and Goat.

Quick Overview for PPIH antibody (Middle Region) (ABIN2784802)

Target: PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPIH Antibody

Binding Specificity: Middle Region

Sequence: DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against PPIH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 177 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIH

Target: PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

Alternative Name: PPIH

Background: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
Alias Symbols: CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP
Protein Interaction Partner: N4BP2L2, HUWE1, UBC, SOX2, METTL18, BAG2, PRPF4, VCAM1, ITGA4, FN1, PAXIP1, PCMT1, PRPF31, PPIH, PRPF3, NHP2L1, CUL3, Prpf8, MEPCE, USP15, SART3, USP4, PRPF18,
Protein Size: 177

Molecular Weight: 19 kDa

Gene ID: 10465

NCBI Accession: NM_006347, NP_006338

UniProt: O43447