HSPH1 antibody (Middle Region)

Catalog No. ABIN503330

The Rabbit Polyclonal anti-HSPH1 antibody has been validated for WB and IHC. It is suitable to detect HSPH1 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit. There is 1 publication available.

Quick Overview for HSPH1 antibody (Middle Region) (ABIN503330)

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HSPH1 Antibody

Binding Specificity: Middle Region

Sequence: EENEMSSEAD MECLNQRPPE NPDTDKNVQQ DNSEAGTQPQ VQTDAQQTSQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HSPH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 858 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSPH1 antibody (ABIN503330)

Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: HSPH1

Background: HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alias Symbols: DKFZp686M05240, HSP105, HSP105A, HSP105B, KIAA0201, NY-CO-25
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, HSPA8, MDM2, ILK, SET, PPM1G, PLOD2, HSPA4, DPYSL2, CTNNA1, PARVA, PUS7, SAMHD1, XPO7, FAF1, CARM1, SEC23A, PRMT3, FARSB, RANBP3, HIRIP3, HIST1H4A, USP11, SF1, UGP2, HECW2, FBXO6, TARDBP, CFTR, METTL21A, env, NOS2, HSP90AB1, HSP9
Protein Size: 858

Molecular Weight: 97 kDa

Gene ID: 10808

NCBI Accession: NM_006644, NP_006635

UniProt: Q92598