HSPH1 antibody (AA 791-840)

Catalog No. ABIN1533311

This Rabbit Polyclonal antibody specifically detects HSPH1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for HSPH1 antibody (AA 791-840) (ABIN1533311)

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HSPH1 Antibody

Binding Specificity: AA 791-840

Purpose: HSP105 Antibody

Specificity: HSP105 Polyclonal Antibody detects endogenous levels of HSP105 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: HSP105

Background:

Synonyms: HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein

Background: function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,

Gene Name: HSPH1

Protein Name: Heat shock protein 105 kDa

Molecular Weight: 96 kDa

Gene ID: 10808

OMIM: 610703

UniProt: Q92598