HSPH1 antibody (Middle Region)

Catalog No. ABIN503330

There is 1 publication for this product available. The Rabbit Polyclonal anti-HSPH1 antibody is suitable to detect HSPH1 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB and IHC.

Quick Overview for HSPH1 antibody (Middle Region) (ABIN503330)

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HSPH1 Antibody

Binding Specificity: Middle Region

Sequence: EENEMSSEAD MECLNQRPPE NPDTDKNVQQ DNSEAGTQPQ VQTDAQQTSQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HSPH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 858 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSPH1 antibody (ABIN503330)

Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: HSPH1

Background: HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alias Symbols: DKFZp686M05240, HSP105, HSP105A, HSP105B, KIAA0201, NY-CO-25
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, HSPA8, MDM2, ILK, SET, PPM1G, PLOD2, HSPA4, DPYSL2, CTNNA1, PARVA, PUS7, SAMHD1, XPO7, FAF1, CARM1, SEC23A, PRMT3, FARSB, RANBP3, HIRIP3, HIST1H4A, USP11, SF1, UGP2, HECW2, FBXO6, TARDBP, CFTR, METTL21A, env, NOS2, HSP90AB1, HSP9
Protein Size: 858

Molecular Weight: 97 kDa

Gene ID: 10808

NCBI Accession: NM_006644, NP_006635

UniProt: Q92598