EHD1 antibody (Middle Region)

Catalog No. ABIN2784845

This Rabbit Polyclonal antibody specifically detects EHD1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for EHD1 antibody (Middle Region) (ABIN2784845)

Target: EHD1 (EH-Domain Containing 1 (EHD1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EHD1 Antibody

Binding Specificity: Middle Region

Sequence: AKKEMVKSKL PNTVLGKIWK LADVDKDGLL DDEEFALANH LIKVKLEGHE

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EHD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EHD1

Target: EHD1 (EH-Domain Containing 1 (EHD1))

Alternative Name: EHD1

Background: This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors.
Alias Symbols: FLJ42622, FLJ44618, H-PAST, HPAST1, PAST, PAST1
Protein Interaction Partner: PLA2G4A, MICALL1, UBC, PDE12, AASDHPPT, CTPS2, UBA6, EHD4, STK39, FKBP9, PDCD10, ATE1, ARIH2, GTF3C4, NOL3, LIMD1, API5, XPNPEP1, WARS, STAT6, PRKDC, PGGT1B, NUBP1, KTN1, DRG2, RBSN, RAB11FIP2, RAB8A, DGKQ, ZFYVE20, MICAL1, ANKFY1, VPS26A, EPN3, EPN1, EHD
Protein Size: 534

Molecular Weight: 60 kDa

Gene ID: 10938

NCBI Accession: NM_006795, NP_006786

UniProt: Q9H4M9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development