ASB8 antibody (N-Term)

Catalog No. ABIN2784915

The Rabbit Polyclonal anti-ASB8 antibody has been validated for WB. It is suitable to detect ASB8 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for ASB8 antibody (N-Term) (ABIN2784915)

Target: ASB8 (Ankyrin Repeat and SOCS Box Containing 8 (ASB8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB8 Antibody

Binding Specificity: N-Term

Sequence: MSSSMWYIMQ SIQSKYSLSE RLIRTIAAIR SFPHDNVEDL IRGGADVNCT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ASB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASB8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB8

Target: ASB8 (Ankyrin Repeat and SOCS Box Containing 8 (ASB8))

Alternative Name: ASB8

Background: ASB8 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: FLJ21255, MGC5540, PP14212
Protein Interaction Partner: NEDD8, SLC25A6, PCNA, ZC3H6, HIF1AN, AMBRA1, KIF26B, TMED10, TUBB3, SLC25A13, CUL5, TCEB2, TCEB1, SERTAD1, RCN1, MCM7, HOXD4,
Protein Size: 288

Molecular Weight: 32 kDa

Gene ID: 140461

NCBI Accession: NM_024095, NP_077000

UniProt: Q9H765