LRG1 antibody (N-Term)

Catalog No. ABIN2784944

This Rabbit Polyclonal antibody specifically detects LRG1 in WB. It exhibits reactivity toward Human, Cow and Pigand has been mentioned in 1 publication.

Quick Overview for LRG1 antibody (N-Term) (ABIN2784944)

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reactivity: Human, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRG1 Antibody

Binding Specificity: N-Term

Sequence: GVTLSPKDCQ VFRSDHGSSI SCQPPAEIPG YLPADTVHLA VEFFNLTHLP

Predicted Reactivity: Cow: 79%, Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against LRG1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LRG1 antibody (ABIN2784944)

OHanlon, Li, Gan, Gourley, Rider, Miller: "Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases." in: Arthritis research & therapy, Vol. 13, Issue 6, pp. R181, (2012) (PubMed).

Target Details for LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Alternative Name: LRG1

Background: The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).
Alias Symbols: HMFT1766, LRG
Protein Interaction Partner: FN1,
Protein Size: 347

Molecular Weight: 38 kDa

Gene ID: 116844

NCBI Accession: NM_052972, NP_443204

UniProt: P02750

Pathways: Brown Fat Cell Differentiation