ASB17 antibody (Middle Region)

Catalog No. ABIN2784968

Product Details anti-ASB17 Antibody

Target: ASB17 (Ankyrin Repeat and SOCS Box Containing 17 (ASB17))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB17 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SPLSGITPLF YVAQTRQSNI FKILLQYGIL EREKNPINIV LTIVLYPSRV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ASB17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB17

Target: ASB17 (Ankyrin Repeat and SOCS Box Containing 17 (ASB17))

Alternative Name: ASB17 (ASB17 Products)

Background: ASB17 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: Asb-17
Protein Interaction Partner: TUBB2B, TUBB, PHB2, RAB10, TUBB4B, TUBB3, TUBA1B, RPL23, VAPA, VDAC1, TUFM, TCEB2, SSR4, SLC25A1, RCN2, HSPB1, CPD, ATP2A2, ARF4, HSP90AA1,
Protein Size: 295

Molecular Weight: 34 kDa

Gene ID: 127247

NCBI Accession: NM_080868, NP_543144

UniProt: Q8WXJ9