DYX1C1 antibody (Middle Region)

Catalog No. ABIN2784980

This anti-DYX1C1 antibody is a Rabbit Polyclonal antibody detecting DYX1C1 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit and Saccharomyces cerevisiae.

Quick Overview for DYX1C1 antibody (Middle Region) (ABIN2784980)

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYX1C1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYX1C1 Antibody

Binding Specificity: Middle Region

Sequence: TDNANARMKA HVRRGTAFCQ LELYVEGLQD YEAALKIDPS NKIVQIDAEK

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DYX1C1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DYX1C1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 420 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYX1C1

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Alternative Name: DYX1C1

Background: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
Alias Symbols: DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD
Protein Interaction Partner: SPDL1, KDM1A, Stub1, Hspa1b, GABARAPL1, GABARAP, HSPA1A,
Protein Size: 420

Molecular Weight: 48 kDa

Gene ID: 161582

NCBI Accession: NM_130810, NP_570722

UniProt: Q8WXU2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling