APBB3 antibody (N-Term)

Catalog No. ABIN2784982

This Rabbit Polyclonal antibody specifically detects APBB3 in WB. It exhibits reactivity toward Human, Rat, Mouse, Guinea Pig, Rabbit, Cow, Dog, Horse and Zebrafish (Danio rerio).

Quick Overview for APBB3 antibody (N-Term) (ABIN2784982)

Target: APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))

Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APBB3 Antibody

Binding Specificity: N-Term

Sequence: SYIQSMEPGA KCFAVRSLGW VEVPEEDLAP GKSSIAVNNC IQQLAQTRSR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against APBB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APBB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 484 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APBB3

Target: APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))

Alternative Name: APBB3

Background: The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: FE65L2, MGC150555, MGC87674, SRA
Protein Interaction Partner: ERBB2, EGFR, APP, RAB4A, APLP2, APLP1,
Protein Size: 484

Molecular Weight: 52 kDa

Gene ID: 10307

NCBI Accession: NM_133174, NP_573420

UniProt: O95704