DEDD2 antibody (Middle Region)

Catalog No. ABIN2784985

The Rabbit Polyclonal anti-DEDD2 antibody (ABIN2784985) specifically detects DEDD2 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig and Horse samples.

Quick Overview for DEDD2 antibody (Middle Region) (ABIN2784985)

Target: DEDD2 (Death Effector Domain Containing 2 (DEDD2))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DEDD2 Antibody

Binding Specificity: Middle Region

Sequence: PQQQSEPARP SSEGKVTCDI RLRVRAEYCE HGPALEQGVA SRRPQALARQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DEDD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DEDD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEDD2

Target: DEDD2 (Death Effector Domain Containing 2 (DEDD2))

Alternative Name: DEDD2

Background: DEDD2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. DEDD2 may regulate degradation of intermediate filaments during apoptosis. DEDD2 may play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Alias Symbols: FLAME-3
Protein Interaction Partner: CDCA7L, ATG16L1, CDK6, RBFOX2, NR2E3, HNRNPAB, RHOXF2, GTF3C3, DEDD2, DEDD, CFLAR, CASP8, CASP10,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 162989

NCBI Accession: NM_133328, NP_579874

UniProt: Q8WXF8