STARD4 antibody (Middle Region)

Catalog No. ABIN2785040

This anti-STARD4 antibody is a Rabbit Polyclonal antibody detecting STARD4 in WB. Suitable for Human, Mouse, Rabbit, Cow, Guinea Pig, Horse, Pig, Rat, Dog and Zebrafish (Danio rerio).

Quick Overview for STARD4 antibody (Middle Region) (ABIN2785040)

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Reactivity: Human, Mouse, Rabbit, Cow, Guinea Pig, Horse, Pig, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STARD4 Antibody

Binding Specificity: Middle Region

Sequence: CCVMRYTTAG QLWNIISPRE FVDFSYTVGY KEGLLSCGIS LDWDEKRPEF

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against STARD4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STARD4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 205 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Alternative Name: STARD4

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Alias Symbols: -
Protein Interaction Partner: UBC,
Protein Size: 205

Molecular Weight: 23 kDa

Gene ID: 134429

NCBI Accession: NM_139164, NP_631903

UniProt: Q96DR4