DUSP10 antibody (N-Term)

Catalog No. ABIN2785082

The Rabbit Polyclonal anti-DUSP10 antibody has been validated for WB. It is suitable to detect DUSP10 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for DUSP10 antibody (N-Term) (ABIN2785082)

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP10 Antibody

Binding Specificity: N-Term

Sequence: MQRLNIGYVI NVTTHLPLYH YEKGLFNYKR LPATDSNKQN LRQYFEEAFE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DUSP10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DUSP10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 140 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DUSP10 antibody (ABIN2785082)

Teng, Huang, Meng: "Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress." in: The Journal of biological chemistry, Vol. 282, Issue 39, pp. 28395-407, (2007) (PubMed).

Target Details for DUSP10

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Alternative Name: DUSP10

Background: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associat
Alias Symbols: MKP-5, MKP5
Protein Interaction Partner: SLX1B, SNX2, RPS11, HTT, FN1, FHL2, MAPK8, CMTM6, MAPK14, MAPK11, MAPK10, MAPK3, MAPK9,
Protein Size: 140

Molecular Weight: 16 kDa

Gene ID: 11221

NCBI Accession: NM_144728, NP_653329

UniProt: D3DTB4