GRPEL2 antibody (Middle Region)

Catalog No. ABIN2785166

The Rabbit Polyclonal anti-GRPEL2 antibody (ABIN2785166) specifically detects GRPEL2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio) samples.

Quick Overview for GRPEL2 antibody (Middle Region) (ABIN2785166)

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRPEL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRPEL2 Antibody

Binding Specificity: Middle Region

Sequence: HEHELICHVP AGVGVQPGTV ALVRQDGYKL HGRTIRLARV EVAVESQRRL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GRPEL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRPEL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 225 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRPEL2

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Alternative Name: GRPEL2

Background: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Alias Symbols: DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Protein Interaction Partner: ELAVL1, UBC, HSPA4,
Protein Size: 225

Molecular Weight: 25 kDa

Gene ID: 134266

NCBI Accession: NM_152407, NP_689620

UniProt: Q8TAA5