PLEKHA7 antibody (Middle Region)

Catalog No. ABIN2785337

The Rabbit Polyclonal anti-PLEKHA7 antibody (ABIN2785337) specifically detects PLEKHA7 in WB. The antibody is reactive with Human, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat and Cow samples.

Quick Overview for PLEKHA7 antibody (Middle Region) (ABIN2785337)

Target: PLEKHA7 (Pleckstrin Homology Domain Containing, Family A Member 7 (PLEKHA7))

Reactivity: Human, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHA7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLEKHA7 Antibody

Binding Specificity: Middle Region

Sequence: PESRYQTLPG RGLSGSTSRL QQSSTIAPYV TLRRGLNAES SKATFPRPKS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PLEKHA7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLEKHA7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1121 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLEKHA7

Target: PLEKHA7 (Pleckstrin Homology Domain Containing, Family A Member 7 (PLEKHA7))

Alternative Name: PLEKHA7

Background: PLEKHA7 is required for zonula adherens biogenesis and maintenance.PLEKHA7 acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
Alias Symbols: DKFZp686M22243
Protein Interaction Partner: LATS2, YWHAB, YWHAQ, UBC, USP20,
Protein Size: 1121

Molecular Weight: 127 kDa

Gene ID: 144100

NCBI Accession: NM_175058, NP_778228

UniProt: Q6IQ23

Pathways: Cell-Cell Junction Organization