PLEKHA7 antibody (Middle Region)

Catalog No. ABIN2785337

Product Details anti-PLEKHA7 Antibody

Target: PLEKHA7 (Pleckstrin Homology Domain Containing, Family A Member 7 (PLEKHA7))

Binding Specificity: Middle Region

Reactivity: Human, Rabbit, Rat, Dog, Guinea Pig, Horse, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHA7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PESRYQTLPG RGLSGSTSRL QQSSTIAPYV TLRRGLNAES SKATFPRPKS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PLEKHA7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLEKHA7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1121 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLEKHA7

Target: PLEKHA7 (Pleckstrin Homology Domain Containing, Family A Member 7 (PLEKHA7))

Alternative Name: PLEKHA7 (PLEKHA7 Products)

Background: PLEKHA7 is required for zonula adherens biogenesis and maintenance.PLEKHA7 acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
Alias Symbols: DKFZp686M22243
Protein Interaction Partner: LATS2, YWHAB, YWHAQ, UBC, USP20,
Protein Size: 1121

Molecular Weight: 127 kDa

Gene ID: 144100

NCBI Accession: NM_175058, NP_778228

UniProt: Q6IQ23

Pathways: Cell-Cell Junction Organization