ASB6 antibody (Middle Region)

Catalog No. ABIN2785356

This Rabbit Polyclonal antibody specifically detects ASB6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig and Horse.

Quick Overview for ASB6 antibody (Middle Region) (ABIN2785356)

Target: ASB6 (Ankyrin Repeat and SOCS Box Containing 6 (ASB6))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB6 Antibody

Binding Specificity: Middle Region

Sequence: LKMAELGLTR AADVLLRHGA NLNFEDPVTY YTALHIAVLR NQPDMVELLV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ASB6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB6

Target: ASB6 (Ankyrin Repeat and SOCS Box Containing 6 (ASB6))

Alternative Name: ASB6

Background: ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.
Alias Symbols: FLJ20548, MGC1024
Protein Interaction Partner: FAM9B, L3MBTL3, RNF41, CADPS2, HIF1AN, ASB3, RNF7, CUL5, TCEB2, HSPB1, FGG, FGB, FGA, SLC25A5, OGFOD1, MCTS1, PROSC, XPNPEP1, EZR, HDGF, FH, ATIC, HSP90AA1, APP, UBD, UBC, DCUN1D1, COPS5, CUL4B, TCEB1, ELAVL1, SH2B2,
Protein Size: 421

Molecular Weight: 46 kDa

Gene ID: 140459

NCBI Accession: NM_017873, NP_060343

UniProt: Q9NWX5