NHEDC2 antibody (C-Term)

Catalog No. ABIN2785368

The Rabbit Polyclonal anti-NHEDC2 antibody has been validated for WB. It is suitable to detect NHEDC2 in samples from Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Pig and Rabbit.

Quick Overview for NHEDC2 antibody (C-Term) (ABIN2785368)

Target: NHEDC2 (Na+/H+ Exchanger Domain Containing 2 (NHEDC2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHEDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NHEDC2 Antibody

Binding Specificity: C-Term

Sequence: IFISFAWLPK ATVQAAIGSV ALDTARSHGE KQLEDYGMDV LTVAFLSILI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NHEDC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NHEDC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 537 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NHEDC2

Target: NHEDC2 (Na+/H+ Exchanger Domain Containing 2 (NHEDC2))

Alternative Name: NHEDC2

Background: Sodium hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce environmental signals into cell responses, or function in drug efflux.Sodium hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce environmental signals into cell responses, or function in drug efflux (Xiang et al., 2007 [PubMed 18000046]).[supplied by OMIM].
Alias Symbols: FLJ23984, NHA2, NHE10, NHEDC2
Protein Interaction Partner: UBC,
Protein Size: 537

Molecular Weight: 57 kDa

Gene ID: 133308

NCBI Accession: NM_178833, NP_849155

UniProt: Q86UD5

Pathways: Proton Transport