ASB7 antibody (Middle Region)

Catalog No. ABIN2785404

This Rabbit Polyclonal antibody specifically detects ASB7 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for ASB7 antibody (Middle Region) (ABIN2785404)

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB7 Antibody

Binding Specificity: Middle Region

Sequence: QTPLHLSALR DDVLCARMLY NYGADTNTRN YEGQTPLAVS ISISGSSRPC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ASB7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB7

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Alternative Name: ASB7

Background: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Alias Symbols: FLJ22551
Protein Interaction Partner: HMBOX1, CCDC136, HIF1AN, ASB4, GANAB, CCT7, RNF7, CUL5, VCL, TCEB2, TCEB1, FGG, FGB, FGA, ATF4, UBD, SRRM1,
Protein Size: 318

Molecular Weight: 36 kDa

Gene ID: 140460

NCBI Accession: NM_198243, NP_937886

UniProt: Q9H672