CDKN3 antibody (C-Term)

Catalog No. ABIN2785489

The Rabbit Polyclonal anti-CDKN3 antibody has been validated for WB. It is suitable to detect CDKN3 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Cow.

Quick Overview for CDKN3 antibody (C-Term) (ABIN2785489)

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDKN3 Antibody

Binding Specificity: C-Term

Sequence: CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CDKN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDKN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 212 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Alternative Name: CDKN3

Background: CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625
Protein Interaction Partner: CDK2, UBC, NCOA3, MS4A3, CDKN3, CDK3, CDC25A, CDK1, CEBPA,
Protein Size: 212

Molecular Weight: 23 kDa

Gene ID: 1033

NCBI Accession: NM_005192, NP_005183

UniProt: Q16667