CDKN3 antibody (AA 1-172)

Catalog No. ABIN3022822

The Rabbit Polyclonal anti-CDKN3 antibody (ABIN3022822) specifically detects CDKN3 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for CDKN3 antibody (AA 1-172) (ABIN3022822)

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDKN3 Antibody

Binding Specificity: AA 1-172

Sequence: MKPPSSIQTS CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CDKN3 (NP_001124323.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Alternative Name: CDKN3

Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CDKN3,CDI1,CIP2,KAP,KAP1,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,CD markers,CDKN3

Molecular Weight: 19 kDa/23 kDa

Gene ID: 1033

UniProt: Q16667