PDHA2 antibody (N-Term)

Catalog No. ABIN2785491

The Rabbit Polyclonal anti-PDHA2 antibody (ABIN2785491) specifically detects PDHA2 in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for PDHA2 antibody (N-Term) (ABIN2785491)

Target: PDHA2 (PDHa2) (Pyruvate Dehydrogenase (Lipoamide) alpha 2 (PDHa2))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDHA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDHA2 Antibody

Binding Specificity: N-Term

Sequence: RMELKADQLY KQKFIRGFCH LCDGQEACCV GLEAGINPSD HVITSYRAHG

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PDHA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDHA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDHA2

Target: PDHA2 (PDHa2) (Pyruvate Dehydrogenase (Lipoamide) alpha 2 (PDHa2))

Alternative Name: PDHA2

Background: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Alias Symbols: MGC149517, MGC149518, PDHAL
Protein Interaction Partner: MSMO1, HNRNPU, DLAT, CAND1, COPS5, CUL3, PDHB,
Protein Size: 388

Molecular Weight: 43 kDa

Gene ID: 5161

NCBI Accession: NM_005390, NP_005381

UniProt: P29803

Pathways: Warburg Effect