ISYNA1 antibody (N-Term)

Catalog No. ABIN2785533

This Rabbit Polyclonal antibody specifically detects ISYNA1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse and Saccharomyces cerevisiae.

Quick Overview for ISYNA1 antibody (N-Term) (ABIN2785533)

Target: ISYNA1 (Inositol-3-Phosphate Synthase 1 (ISYNA1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ISYNA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ISYNA1 Antibody

Binding Specificity: N-Term

Sequence: LQEQLWPHME ALRPRPSVYI PEFIAANQSA RADNLIPGSR AQQLEQIRRD

Predicted Reactivity: Cow: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 86%, Yeast: 92%

Characteristics: This is a rabbit polyclonal antibody against ISYNA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ISYNA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 558 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ISYNA1

Target: ISYNA1 (Inositol-3-Phosphate Synthase 1 (ISYNA1))

Alternative Name: ISYNA1

Background: Myoinositol, the most common naturally occurring form of inositol, is a component of plasma membrane phospholipids and functions as a cell signaling molecule. ISYNA1 (EC 5.5.1.4), or IPS, is a rate-limiting enzyme that catalyzes the de novo synthesis of myoinositol 1-phosphate from glucose 6-phosphate.Myoinositol, the most common naturally occurring form of inositol, is a component of plasma membrane phospholipids and functions as a cell signaling molecule. ISYNA1 (EC 5.5.1.4), or IPS, is a rate-limiting enzyme that catalyzes the de novo synthesis of myoinositol 1-phosphate from glucose 6-phosphate (Seelan et al., 2004 [PubMed 15464731]).[supplied by OMIM].
Alias Symbols: IPS, INO1, INOS, IPS 1, IPS-1
Protein Interaction Partner: TRAF4, UBC, DUSP14, POT1, PPP2CA,
Protein Size: 558

Molecular Weight: 61 kDa

Gene ID: 51477

NCBI Accession: NM_016368, NP_057452

UniProt: Q9NPH2