SPA17 antibody (N-Term)

Catalog No. ABIN2785535

This Rabbit Polyclonal antibody specifically detects SPA17 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Sheep, Dog, Pig and Zebrafish (Danio rerio).

Quick Overview for SPA17 antibody (N-Term) (ABIN2785535)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Sheep, Dog, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPA17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPA17 Antibody

Binding Specificity: N-Term

Sequence: MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SPA17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPA17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 151 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Alternative Name: SPA17

Background: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
Alias Symbols: SP17, SP17-1, CT22
Protein Interaction Partner: MYL6B, ROPN1, AKAP7, UBC, ROPN1B, AKAP3,
Protein Size: 151

Molecular Weight: 17 kDa

Gene ID: 53340

NCBI Accession: NM_017425, NP_059121

UniProt: Q15506