TSKS antibody (Middle Region)

Catalog No. ABIN2785556

This Rabbit Polyclonal antibody specifically detects TSKS in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Rabbit and Horse.

Quick Overview for TSKS antibody (Middle Region) (ABIN2785556)

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSKS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSKS Antibody

Binding Specificity: Middle Region

Sequence: ALRLLGGLGG RVDGFLGQWE RAQREQAQTA RDLQELRGRA DELCTMVERS

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TSKS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSKS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSKS

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Alternative Name: TSKS

Background: TSKS may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the TSKS is highest in the testis and down-regulated in testicular cancer. The gene encoded TSKS is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.
Alias Symbols: TSKS1, TSSKS, STK22S1
Protein Interaction Partner: PPP1CA, SF3A3, SF3A1, USP10, APP, TSSK2,
Protein Size: 592

Molecular Weight: 65 kDa

Gene ID: 60385

NCBI Accession: NM_021733, NP_068379

UniProt: Q9UJT2

Pathways: Toll-Like Receptors Cascades