EPHX1 antibody (Middle Region)
Quick Overview for EPHX1 antibody (Middle Region) (ABIN2785633)
Target
See all EPHX1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- CPSIPGYGFS EASSKKGFNS VATARIFYKL MLRLGFQEFY IQGGDWGSLI
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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Characteristics
- This is a rabbit polyclonal antibody against EPHX1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human EPHX1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 455 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EPHX1 (Epoxide Hydrolase 1, Microsomal (Xenobiotic) (EPHX1))
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Alternative Name
- EPHX1
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Background
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Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Epoxide hydrolase plays an important role in both the activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EPHX, EPOX, MEH, HYL1
Protein Interaction Partner: RNF2, ATP4A, UBC, HPDL, CDKN2AIP, DNAJB11, SUMO1,
Protein Size: 455 -
Molecular Weight
- 53 kDa
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Gene ID
- 2052
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NCBI Accession
- NM_000120, NP_000111
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UniProt
- P07099
Target
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