ALOX12 antibody (C-Term)

Catalog No. ABIN2785665

This Rabbit Polyclonal antibody specifically detects ALOX12 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for ALOX12 antibody (C-Term) (ABIN2785665)

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALOX12 Antibody

Binding Specificity: C-Term

Sequence: MGSLPDVRQA CLQMAISWHL SRRQPDMVPL GHHKEKYFSG PKPKAVLNQF

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ALOX12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALOX12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 663 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALOX12

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Alternative Name: ALOX12

Background: ALOX12 belongs to the lipoxygenase family. It contains 1 lipoxygenase domain and 1 PLAT domain. It has oxygenase and 14,15-leukotriene A4 synthase activity.
Alias Symbols: 12-LOX, LOG12, 12S-LOX
Protein Interaction Partner: ACTA2, ALOX12, TRIB1, KRT85, KAT5, PLA2G2A, LMNA, KRT5, ITGB4,
Protein Size: 663

Molecular Weight: 76 kDa

Gene ID: 239

NCBI Accession: NM_000697, NP_000688

UniProt: P18054

Pathways: Positive Regulation of Endopeptidase Activity