DBNL antibody (Middle Region)

Catalog No. ABIN2785712

The Rabbit Polyclonal anti-DBNL antibody has been validated for WB. It is suitable to detect DBNL in samples from Human, Mouse, Dog and Guinea Pig.

Quick Overview for DBNL antibody (Middle Region) (ABIN2785712)

Target: DBNL (Drebrin-Like (DBNL))

Reactivity: Human, Mouse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBNL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DBNL Antibody

Binding Specificity: Middle Region

Sequence: QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE

Predicted Reactivity: Dog: 100%, Guinea Pig: 79%, Human: 100%, Mouse: 86%

Characteristics: This is a rabbit polyclonal antibody against DBNL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DBNL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 430 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DBNL

Target: DBNL (Drebrin-Like (DBNL))

Alternative Name: DBNL

Background: DBNL is an actin-binding adapter protein. DBNL may act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. DBNL acts as a k
Alias Symbols: ABP1, HIP-55, SH3P7
Protein Interaction Partner: SH2D4A, UBC, UBE3A, RANGAP1, LPP, LRSAM1, C14orf142, UBA5, P3H1, PPME1, TPRKB, ERO1L, HSPBP1, GPN1, WDR4, PLIN3, OGT, AGFG1, DR1, DDX5, CBS, ALAD, BMH1, BAG3, CUL1, ACD, TERF2IP, POT1, TERF1, SH3BP2, LMNA, CBL, KDM5B, NEURL4, DBNL, MAP4K1, SYK, ZAP70, CAS
Protein Size: 430

Molecular Weight: 48 kDa

Gene ID: 28988

NCBI Accession: NM_001014436, NP_001014436

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization