Arylsulfatase A antibody (N-Term)

Catalog No. ABIN2785757

This Rabbit Polyclonal antibody specifically detects Arylsulfatase A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Horse, Dog and Guinea Pig.

Quick Overview for Arylsulfatase A antibody (N-Term) (ABIN2785757)

Target: Arylsulfatase A (ARSA)

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arylsulfatase A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Arylsulfatase A Antibody

Binding Specificity: N-Term

Sequence: DLGCYGHPSS TTPNLDQLAA GGLRFTDFYV PVSLCTPSRA ALLTGRLPVR

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARSA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARSA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 507 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Arylsulfatase A

Target: Arylsulfatase A (ARSA)

Alternative Name: ARSA

Background: ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD).The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.
Alias Symbols: MLD
Protein Interaction Partner: TRIP13, PPIC, CETN2, CLEC4G, ARSA, GAL3ST1, BMPR2, CTSL,
Protein Size: 507

Molecular Weight: 56 kDa

Gene ID: 410

NCBI Accession: NM_000487, NP_000478

UniProt: P15289