ACADSB antibody (Middle Region)

Catalog No. ABIN2785786

The Rabbit Polyclonal anti-ACADSB antibody has been validated for WB. It is suitable to detect ACADSB in samples from Human, Rat, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae.

Quick Overview for ACADSB antibody (Middle Region) (ABIN2785786)

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Reactivity: Human, Rat, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADSB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACADSB Antibody

Binding Specificity: Middle Region

Sequence: GLRASSTCPL TFENVKVPEA NILGQIGHGY KYAIGSLNEG RIGIAAQMLG

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ACADSB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACADSB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACADSB

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Alternative Name: ACADSB

Background: Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. ACADSB has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs.Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7- kDa. Sequence Note: The 3' UTR extension represented by the RefSeq transcript record was derived from genomic sequence data to optimize consistency to the reference genome assembly. The extent of the UTR extension and the location of the polyA site was based on transcript alignments.
Alias Symbols: 2-MEBCAD, ACAD7, SBCAD
Protein Interaction Partner: SUMO2, UBD, UBC, USP19,
Protein Size: 432

Molecular Weight: 44 kDa

Gene ID: 36

NCBI Accession: NM_001609, NP_001600

UniProt: P45954

Pathways: Monocarboxylic Acid Catabolic Process