FKBP5 antibody (Middle Region)

Catalog No. ABIN2785845

This Rabbit Polyclonal antibody specifically detects FKBP5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig and Pig.

Quick Overview for FKBP5 antibody (Middle Region) (ABIN2785845)

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP5 Antibody

Binding Specificity: Middle Region

Sequence: KMQREEQCIL YLGPRYGFGE AGKPKFGIEP NAELIYEVTL KSFEKAKESW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FKBP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FKBP5

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites.
Alias Symbols: AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Protein Interaction Partner: LRRC40, CXorf57, EGLN1, AGO2, CACYBP, CHORDC1, AGO1, KIAA1279, NUDCD3, GLMN, CDC37, SUGT1, PTGES3, NUDC, AHSA1, DNAJB6, AURKB, IKBKG, IRS4, TUBA1A, TTC4, PYGL, PDCD2, CDK11A, HGH1, C14orf80, MCMBP, PNPLA2, ANKMY2, CDC37L1, MCM4, ILK, HSP90AB1, HSP90AA1, H
Protein Size: 457

Molecular Weight: 51 kDa

Gene ID: 2289

NCBI Accession: NM_004117, NP_004108

UniProt: Q13451