GBP2 antibody (N-Term)

Catalog No. ABIN2785847

The Rabbit Polyclonal anti-GBP2 antibody is suitable to detect GBP2 in samples from Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog and Horse. It has been validated for WB.

Quick Overview for GBP2 antibody (N-Term) (ABIN2785847)

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GBP2 Antibody

Binding Specificity: N-Term

Sequence: HTKGIWMWCV PHPKKPEHTL VLLDTEGLGD IEKGDNENDS WIFALAILLS

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 591 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2

Background: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Alias Symbols: -
Protein Interaction Partner: CNDP2, NANS, RPS6KA1, PEPD, MVD, GSR, GNS, GLA, G6PD, CASP7, CAPN1, ASS1, GSK3B, GADD45A, CSNK2B, BNIP3L, BID, ANXA7, MAPK8IP2, STK3, KLHL20, BTBD2, LSM2, PAFAH1B3, PPP1R8, MAGI1, TFG, SERPINB9, SEPHS1, FXR1, HSPE1, SAT1,
Protein Size: 591

Molecular Weight: 67 kDa

Gene ID: 2634

NCBI Accession: NM_004120, NP_004111

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin