HADH antibody (C-Term)

Catalog No. ABIN2785872

This anti-HADH antibody is a Rabbit Polyclonal antibody detecting HADH in WB and IHC. Suitable for Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Cow and Saccharomyces cerevisiae.

Quick Overview for HADH antibody (C-Term) (ABIN2785872)

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HADH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HADH Antibody

Binding Specificity: C-Term

Sequence: YPMGPFELLD YVGLDTTKFI VDGWHEMDAE NPLHQPSPSL NKLVAENKFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HADH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HADH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HADH

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Alternative Name: HADH

Background: HADH functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HAD, HADH1, HADHSC, HHF4, M/SCHAD, MGC8392, SCHAD, HCDH, MSCHAD
Protein Interaction Partner: MDM2, STAT1, ADH1A, APP, UBC, MAPK3, UBA5, HADH, SLC2A4,
Protein Size: 314

Molecular Weight: 33 kDa

Gene ID: 3033

NCBI Accession: NM_005327, NP_005318

UniProt: Q16836

Pathways: Negative Regulation of Hormone Secretion, Monocarboxylic Acid Catabolic Process