CASC3 antibody (N-Term)

Catalog No. ABIN2785902

This anti-CASC3 antibody is a Rabbit Polyclonal antibody detecting CASC3 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for CASC3 antibody (N-Term) (ABIN2785902)

Target: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CASC3 Antibody

Binding Specificity: N-Term

Sequence: MADRRRQRAS QDTEDEESGA SGSDSGGSPL RGGGSCSGSA GGGGSGSLPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CASC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CASC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CASC3

Target: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Alternative Name: CASC3

Background: The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts w
Alias Symbols: BTZ, MLN51
Protein Interaction Partner: UBC, BMI1, env, GRB2, CDK6, EIF4A3, MAGOH, CAND1, ELAVL1, STAU1,
Protein Size: 703

Molecular Weight: 76 kDa

Gene ID: 22794

NCBI Accession: NM_007359, NP_031385

UniProt: O15234