CCT5 antibody (C-Term)

Catalog No. ABIN2785906

This Rabbit Polyclonal antibody specifically detects CCT5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Rabbit, Dog, Guinea Pig and Horse.

Quick Overview for CCT5 antibody (C-Term) (ABIN2785906)

Target: CCT5 (Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCT5 Antibody

Binding Specificity: C-Term

Sequence: DCLHKGTNDM KQQHVIETLI GKKQQISLAT QMVRMILKID DIRKPGESEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against CCT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 541 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT5

Target: CCT5 (Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5))

Alternative Name: CCT5

Background: CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CCT-epsilon, CCTE, KIAA0098, TCP-1-epsilon
Protein Interaction Partner: SSSCA1, HUWE1, UBC, TP53, FUS, TUBG1, SUMO2, SUMO3, LGALS3BP, CDC20, NEDD1, MDM2, RNF2, CCT8, CCT2, CCT7, FBXO6, UBD, TERT, FBXW4, CDK9, CDK5, HDAC6, HDAC3, ILK, CDK2, PAN2, FAM86B2, PEX14, NOS2, ITGA4, FN1, ATF2, METTL21B, VCAM1, VCP, PACRG, AHCYL1, CCT6
Protein Size: 541

Molecular Weight: 60 kDa

Gene ID: 22948

NCBI Accession: NM_012073, NP_036205

UniProt: P48643