MTO1 antibody (N-Term)

Catalog No. ABIN2785915

This Rabbit Polyclonal antibody specifically detects MTO1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for MTO1 antibody (N-Term) (ABIN2785915)

Target: MTO1

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTO1 Antibody

Binding Specificity: N-Term

Sequence: STVYAESVIL TTGTFLRGMI VIGLETHPAG RLGDQPSIGL AQTLEKLGFV

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MTO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MTO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 732 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTO1

Target: MTO1

Background: MTO1 is a mitochondrial protein thought to be involved in mitochondrial tRNA modification. It may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene.This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CGI-02
Protein Interaction Partner: UBC, KDM1A, SUV39H1,
Protein Size: 732

Molecular Weight: 81 kDa

Gene ID: 25821

NCBI Accession: NM_001123226, NP_001116698

UniProt: Q9Y2Z2